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Additionally, in mice carrying APOE4, stress induces a loss of GABAergic neurons in the prefrontal cortex and hippocampal dentate gyrus, which may contribute to an increased risk of depression (Zhang J

2.2.5 Peroxisomes: modulators of lipid oxidation and antioxidant defense Peroxisomes regulate lipid metabolism and ROS detoxification, influencing ferroptosis (79)