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The MRM/MS was performed as previously described 52

This proposed data collection was similar to the market-based data collection as finalized in the FY 2021 IPPS/LTCH PPS final rule (85 FR 558873 through 58892), with additional modifications to use the payer-specific negotiated charges from the hospital's most recent MRF published prior to the submission of its cost report, to reflect proposed revisions to the hospital price transparency regulations at 45 CFR 180, and to better address when the payer-specific negotiated charge is based on a percentage or algorithm, in response to previous concerns (85 FR 58884)

The injection delivers B12 directly into the bloodstream, making it the most reliable method for patients with absorption problems, pernicious anaemia, or gastrointestinal conditions affecting B12 uptake (such as Crohn's disease, coeliac disease, or following gastric surgery)