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Furthermore, there are drug interactions, particularly noted among online communities like Longecity, against the concurrent use of FOXO4-DRI with certain compounds such as Rapamycin, Quercetin, corticosteroids, and cortisol, due to potential interactions that might diminish the peptide's senolytic efficacy

- Dosage: 100 mcg to 300 mcg, taken 2-3 times daily

Tesofensine has even been called a novel potent weight loss medicine by the Queensland University of Technology and has shown minimal side effects

The therapy helps patients feel an increase in energy the same day, while other benefits appear with repeated sessions