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CRISPR/Cas9-mediated knockout of C32E8.9 To generate a knockout of the C32E8.9 gene in C

It upregulates the expression of Pink1, Parkin, Bnip3 and BCL2 like 13 (Bcl2l13) proteins and LC3B-II/I ratio, promotes mitophagy in the skeletal muscle of mdx52 mice, and significantly inhibits the expression of inflammatory and OS marker proteins (CD68, CD206, SOD1, and SOD2), which in turn improve the anti-fatigue ability of skeletal muscle of mdx52 mice

Wei W, Jiang W, Tian Z, Wu H, Ning H, Yan G, Zhang Z, Li Z, Dong F, Sun Y, Li Y, Han T, Wang M, Sun C (2021) Fecal g

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