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Description

February, 2012

Intraperitoneal administration of carbon tetrachloride induced significantly more severe liver injury in Aadac knockout (KO) mice (plasma alanine aminotransferase level: 19,381 10,578 U/L) than in wild-type (WT) mice (7219 4729 U/L)

Conclusion: Platelet count, APRI, and FIB-4 are inexpensive, readily available tools to identify patients with liver cirrhosis who are at higher risk for liver decompensation