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mEPSCs were recorded in the presence of tetrodotoxin (1 M, Tocris, Ellisville, MO, USA or Alomone, Jerusalem, Israel) and picrotoxin (0.1mM, Sigma-Aldrich, St

Years later, Hopkins concluded that philothion and glutathione (GSH) were identical and, after several studies, in 1935, its structure was established as a tripeptide, composed of glutamic acid, cysteine and glycine [1,3]

Conversely, efficient metabolic transitions can benefit health and influence lifespan, as evidenced by reduced disease incidence and prolonged lifespan associated with fasting 2,3,4,5,6