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These iron ions can exacerbate oxidative stress by catalyzing Fenton and Haber-Weiss reactions, leading to the production of ROS and reactive nitrogen species, which subsequently cause damage to brain cells (Fila et al., 2024)

doi: 10.1038/s41568-022-00513-x 77 RoutyBLenehanJGMillerWHJr.JamalRMessaoudeneMDaisleyBAet al

The FOX1 method was notably employed by Hull and colleagues and revealed a significant elevation in lipid hydroperoxide concentrations in the ELF of CF patients exhibiting inflammation, compared to both the control group and the CF group without inflammation

The in-utero exposure to other endocrine-disrupting chemicals, such as polybrominated biphenyls (PBBs) and dichlorodiphenyldichloroethylene (DDE), and their correlations with earlier age of menarche, have also been reported ( in-utero ATZ exposure, may point to a promising direction for future research