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Results: Of the 63 patients, the mean age was 49 years, 65% were male, 17% were cirrhotic, 67% were treated with ETV, and the median treatment duration was 3 years

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Conclusion: This study demonstrated that elevated liver enzymes at baseline were a strong risk driver for liver injury among MS patients

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[PubMed: 11433352] 799

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IGFBPs thus act both as carriers of IGF, prolonging its half-life, and as modulators of IGF availability and activity ( Figure 1E )

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