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(ii) Cu 2+ induces the secretion of acidic SMase from leukocytes which in turn leads to accumulation of erythrocytic ceramide [131] and (iii) treatment of erythrocytes with extracellular SMase resulted in ceramide-associated alterations in membrane-cytoskeleton interactions and membrane organization [125]

(2010) compared and discovered significantly higher IL-6 levels in PD patients than those in controls, and that the PD patients with relatively higher IL-6 levels had a slower stride and were more prone to fatigue

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