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Researchers choose MOTS-c when they need a precise tool for studying mitochondrial-to-nuclear signaling , energy metabolism, and aging-related pathways

doi: 10.1016/j.biopha.2021.111576 303 SjaardaLAMumfordSLKuhrDLHollandTLSilverRMPlowdenTCet al

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4.1 Limitations of the study In this study, we demonstrate that Rab12, a known physiological substrate of LRRK2, can also be phosphorylated in a LRRK1 and PKC-dependent manner