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Despite these advances, challenges remain, such as model interpretability, standardization across cohorts, and prospective validation

303 Targeting mitochondrial metabolism Targeting mitochondrial metabolism further intersects with mitophagy modulation

Resistance can manifest as intrinsic resistance, where cancer cells are inherently unresponsive to treatment, or acquired resistance, which develops due to selective pressures during therapy

Plants grown on contaminated soils may accumulate heavy metals in aerial parts such as leaf tissues and seeds and can result in severe health consequences for foraging animals and humans if these metals enter the food supply (Peralta-Videa et al., 2009)