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Standard laboratory practice is refrigeration at 28C for medium-term storage, or freezing at 20C or below for long-term, with the vial protected from light and moisture

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Histopathological analysis of animals challenged with Wuhan strain and different variants showed that vaccinated mice and hamsters had preserved lung structure, reduced inflammatory infiltrate, pro-inflammatory cytokines and chemokines levels compatible with controlled viral replication, as compared to non-vaccinated animals