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Description

The Journal of the American Academy of Orthopaedic Surgeons

Journal of Clinical Endocrinology & Metabolism , 91(3), 799805

10.1111/odi.12961 96

A preclinical pilot study in human patients with chronic pain episodes found, that DSIP significantly reduced pain perception, also improved mood by reduction of depressive states, and that it may potentially be of interest for research into physiological addiction on pain medications, as it was observed to reduce withdrawal symptoms that occurs after discontinuation of long-term analgesic treatment