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For example, genes such as LGR5 and LGR6 have been implicated in hair follicle stem cell maintenance and activation, whereas their role in nail physiology is less clear

4 The mineral/salt forms of ascorbic acid, including sodium ascorbate and calcium ascorbate are thought to be less acidic and potentially better tolerated (fewer GI side effects)

5 Common side effects could include: Vertigo/dizziness Abnormal physical weakness Nausea Constipation Appetite changes Weight gain Drowsiness/fatigue Dryness of the mouth Low sodium levels Nightmares Sleep disturbances Sleepwalking, sleep-driving, etc.* Lightheadedness Tachycardia (elevated heart rate at rest) Less common, but more severe adverse effects should be carefully monitored and could include suicidal thoughts (ideation and behavior

doi: 10.1016/j.phymed.2023.155199