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This fermentation process generates various byproducts, among which SCFAs are the core pathway connecting gut microbiota and host metabolic interactions (consistent with the previously mentioned mechanism by which proteins and lipids improve mood through the microbiota-SCFAs axis)

For instance, certain studies have indicated that glutathione levels are lower in individuals with chronic kidney disease, highlighting its potential importance in renal health

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Thus, thiamine, combined with other vitamins of the B complex such as B2 and B3, is vital for the proper functioning of various enzymes involved in key biochemical processes, primarily those related to energy production (34, 36) ( Figure 3 )