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4.1 Future directions: strengths, limitations and potential therapeutic interventions All literature highlighted and discussed in this review highlights some of the research that has been conducted examining the relationship between mitochondria and the gut microbiome, but it is clear that further research is required before we can utilize this relationship as a therapeutic intervention in primary mitochondrial diseases

In some private weight management settings, Lipo C injections and investigational agents such as retatrutide are occasionally discussed in combination, with the rationale that lipotropic compounds may complement the metabolic effects of receptor agonist therapies

ZX: Data curation, Methodology, Project administration, Resources, Writing original draft

doi: 10.1023/a:1022349623951