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Several viruses, including IAV and HIV-1, utilize mitochondrial apoptosis to facilitate viral spread, although some delay apoptosis early in infection to optimize replication ( 2.5 Viral-induced mtDNA release and cross-talk with innate immune signaling pathways Once released into the cytosol, mitochondrial DNA (mtDNA) functions as a potent DAMP that activates multiple innate immune pathways

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Receptor mechanism and selectivity

This can make it easier to burn fat and maintain a healthy weight