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Description

Conrad, M., Schneider, M., Seiler, A

Final thoughts

In a preferred embodiment of the invention, the crosslinker moiety is connected to backbone moieties by at least two biodegradable bonds

The samples collected for biochemical assays included plasma for Nf-L measures, whole brain tissue and plasma for PK analysis of unbound inhibitor exposure levels, and frontotemporal cortex brain and spinal cord tissues for immunoblotting soluble and insoluble protein fractions (Fig