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In the context of the so-called microbiotagutbrain (MGB) axis, it is shown to have a strong influence on host neuromodulation and endocrine functions (i.e., controlling the synthesis of neurotransmitters like serotonin or mediating the activation of the hypothalamicpituitaryadrenal axis), as well as in modulation of host immune responses, critically regulating intestinal, systemic and brain inflammation (neuroinflammation)

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Patient reports 15% pain reduction, insufficient for functional restoration. Imaging reports correlate symptoms with anatomic findings

The Iron Chelator, Desferrioxamine, Reduces Inflammation and Atherosclerotic Lesion Development in Experimental Mice