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Someone with known heart disease, high blood pressure, previous heart problems or a family history of rhythm issues should take that into account and may need to be more cautious

MK-677 is generally well-tolerated, but in some cases, it may cause mild water retention, which could temporarily elevate blood pressure

The most meaningful differences are how each peptide signals the pituitary, how strong the human evidence is for real outcomes, and whether what youre being offered is FDA-approved, compounded, or research-only (Molitch et al., 2011)