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The results from the study on the prodrugs impact on tumor growth in A549 xenografts show that it is more effective at inhibiting tumor growth in vivo than the unmodified 5-FU compound (Figure 5C)

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However, there are several issues with FMT as follows: biological mechanisms remain undescribed, donor stool will not always be available, risks and side effects remain unclear, and long-term safety data are extremely limited (Liu Y