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Mechanism 3 Direct Fat Cell Targeting (Lipolytic Pathway) Some peptides bypass appetite and hormonal pathways entirely and act directly on fat cells

Principal Investigator on A Randomized, Double-blind, Multicentre, Parallel-group, Placebo-controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Aticaprant 10 mg as Adjunctive Therapy in Adult Participants with Major Depressive Disorder (MDD) with Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy. Principal Investigator on A Study of Disease Characteristics and Real-life Standard of Care Effectiveness in Patients with Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including an SSRI or SNR. (Janssen)

Search strategy: autism spectrum disorder OR ASD AND oxidative OR redox OR mitochondrial OR neuroinflammation AND vitamin C/ascorbate

Park Y, Lee DG, Hahm KS