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Other secondary effects included dysaesthesia, paraesthesias, dry eyes, deafferentation pain, and keratitis.77 However, 2 meta-analyses, including a total of 13 studies (1353 patients), found that, compared with stereotactic radiosurgery, MVD is more effective in short- and long-term pain control (96% vs 71%), presents lower rates of complications and reinterventions, and is less costly

FDA News Release, "FDA Approves New Nasal Spray Medication for Treatment-Resistant Depression," March 2019

Clinical trials and recent meta-analyses consistently show tirzepatide delivers the most substantial weight reduction among GLP-1 medications, with average losses of up to 22.5% of body weight