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Chlorogenic acid Chlorogenic acid (CGA) is a polyphenolic compound found in a wide range of plants, most notably green coffee beans, as well as in numerous foods and beverages [161]

And the ventral tegmental area modulates reward-based eating behavior, essentially reducing the pleasure response to food

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Interestingly, an E-box motif has also been identified in the rat GCLC promoter, but it is present in the region that negatively regulate the GCLC promoter in lung epithelial L2 cells (Cheng et al., 2005)