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doi: 10.1186/s12943-016-0526-2 93 YangFLiJDengHWangYLeiCWangQet al

Targeting virulence: a new paradigm for antimicrobial therapy

These effects force permanent cell cycle exit and disrupt immunosuppressive tumor microenvironment, translating synergistic efficacy against RB -proficient and RB -deficient TNBC, paving the way for new clinical trials to evaluate their clinical impact on patients with TNBC