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Note that the only significant deviation of GSH in Panel B of Figure 2 occurs during days 10-14 when estradiol and S become very high, thus depressing the GSH concentration [Table 1]

In addition, a study conducted by Sizemore et al (140) reveals that the ATM-PKM2-CtIP axis enhances DNA double-stand break repair efficiency and resistance to genotoxic damage caused by radiation