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However, we have previously shown that high doses of vitamin K sufficiently rescued warfarin poisoning in both wild-type and NQO1-deficient mice, and the warfarin-resistant VKR activity (i.e., distinct from VKOR and NQO1) were detected in both wild-type and NQO1-kncokout mice, suggesting that NQO1 was not the warfarin-resistant VKR 52

Activity index = intensity of movement acceleration during a given time

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Furthermore, AZT or the combination AZT plus indinavir (protease inhibitor) induces oxidative stress in human brain microvascular endothelial cells