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In contrast, NF-kB p65 levels were abrogated in cells expressing a gRNA targeting RELA (Cre-R-1 or R-2) only when they were cultured under hypoxia (Fig

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Groups A and B were pre-treated with remote ischaemic conditioning (RIPC, tolerant), while C and D underwent the same procedure without a hind limb tourniquet (non-RIPC, non-tolerant)

Acknowledgements We thank all the members of the Mostoslavsky laboratory for critical discussions throughout the years and editing of the manuscript, especially T