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10.1016/j.ecoenv.2022.114104 136 LiQ

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Neuroprotection Models In neuronal cultures from Alzheimers disease mouse models, SS-31 restored synaptic viability, mitochondrial motility, and mitochondrial transport establishing a role for the compound in investigating A toxicity and neuronal mitochondrial dysfunction

It promotes NRF2 ubiquitination through the Keap1/NRF2/ARE signaling pathway, induces ROS accumulation, and inhibits the phosphorylation of AktSer473 and mTORSer2448