glutathione-mediated reduction of hydrogen peroxide Deciphering the mechanism glutaredoxin-catalyzed roGFP2 redox sensing reveals a ternary complex with glutathione for protein disulfide Frontiers | Research progress of

That this finding was only observed in the DLPFC (and not the ACC) in our cohort is in line with research observing frontal cortical thinning in blast exposed veterans (59), decreased activity (60), and white matter damage (61) in the PFC following mTBI

Moreover, a model of Hutchinson-Gilford progeria syndrome (HGPS) shows larger nucleoli, increased ribosomal biogenesis and an overall increase in protein translation levels (Buchwalter and Hetzer, 2017), thus ascribing a potential functional connection between this aging biomarker and the global increase in protein synthesis that is observed over aging

doi: 10.1017/S003118209600858X 69 NausCWABoothMJonesFMKemijumbiJVennervaldBJKariukiCHet al

It may be interesting to experimentally address such potential synergistic effects, which could be exploited to provide a pathway to the development of new therapeutics against a range of disease-causing enteroviruses