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The immunosuppressive capabilities of tumor-infiltrating myeloid cells and regulatory T (Treg) cells are also regulated by lactylation, involving mechanisms such as RNA methylation modification and signaling enhancement [138,139]

Medications and comorbidities are detailed in Supplementary Table 1

therefore, glyphosate has been considered safe for human health, however, this pathway is present in plants and many microorganisms, including members of the gut microbiota (Mesnage et al., 2021)