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doi:10.1007/3418_004

Long-term, supplemental, one-carbon metabolismrelated vitamin B use in relation to lung cancer risk in the vitamins and lifestyle (VITAL) cohort

While it's known for its powerful fat-releasing (lipolytic) effects, it also influences muscle growth, blood sugar levels, and cellular growth (the IGF-1 pathway)

The NHS hypokalaemia overview explains why it matters, and clinical references such as StatPearls on B12 deficiency treatment specifically flag monitoring potassium during the early loading phase in people who were severely deficient