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Upon CMA activation, an increase in both Nrf2 protein levels and its transcriptional activity is observed

Briefly, we first transfer the proteins symbols to Entrez IDs based on Bioconductor annotation data package (org.Hs.eg.db/org.Mm.eg.db) and used the clusterProfiler::enrichGO or clusterProfiler::gseGO with the pvalueCutoff = 0.05, qvalueCutoff = 0.05 to do pathway enrichment analysis

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