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In the STEP-8 trial, patients taking semaglutide lost an average of around 16% of their body weight, while u003ca href=u0022#who-is-invigor-medical-not-foru0022u003ethose on liraglutide lost only about 6%u003c/au003e.u003csupu003e[9]u003c/supu003e u003cbru003eu003cbru003eBoth medications work by mimicking the GLP-1 hormone to regulate appetite, but semaglutides once-weekly dosing often makes it easier to stick with compared to liraglutides daily injections

The standard maintenance schedule is hydroxocobalamin 1mg intramuscularly every two to three months (or every 2 months if neurological symptoms were present), though some patients require more frequent injections to maintain symptom control

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61 Clinical trials in humans have evaluated the benefits of B12 in a number of painful conditions