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Description

H 2 S causes vascular endothelial and smooth muscle cell hyperpolarization and vasorelaxation by activating K ATP channels through cysteine S-sulfhydration, which can enhance Kir6.1-PIP2 binding and reduce Kir6.1-ATP binding (19)

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In mice, heterozygous mutation of Galntl5 impaired sperm motility, decreased the level of some glycolytic enzymes, disrupted protein loading to the acrosome, and induced aberrant localization of the ubiquitinproteasome machinery