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Description

With the deepened comprehension of molecular mechanism, glutathione peroxidase 4 (GPX4) has been thoroughly reported as a key regulator for protecting cells from toxic lipid hydroperoxides of ferroptosis, which is highly expressed in tumor tissues compared with that in adjacent normal tissues 3,4,5

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Astrocytes and neurons contain glutamine transporters, whichunder appropriate electrophysiological conditionsresult in a net exchange of glutamine between astrocytes and neurons

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