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Specifically, the ability of vitamin C to scavenge free radicals can reduce the degree of oxidative stress and increase the viability of nerve cells in the cerebral cortex and striatum (Ballaz and Rebec, 2019)

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Salidroside (SAL), a natural compound derived from Rhodiolaspecies, has been shown to modulate the Nrf2/GPX4 axis and iron transport, reduce A and iron deposition, and alleviate neuronal damage and cognitive deficits (Yang et al., 2023)