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Furthermore, ABCC5 overexpression increased SLC7A11 expression, decreased lipid peroxidation, and increased intracellular GSH levels, resulting in reduced ferroptosis (91)

Harris, a brilliant English physiologist, and others provided anatomic and physiological evidence in the late 1940s 1 that the hypothalamic portion of the brain controls the secretion of gonadotropins, luteinizing hormone (LH), and the follicle-stimulating hormone (FSH) from the anterior pituitary gland 1

Not only do the etiology and pathophysiology of the non-motor symptoms of PD remain unclear, but the precise mechanism for the death of neurons in PD is also uncertain

Grgens C, Guddat S, Thomas A, Thevis M