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It is produced in the photosynthesizing cells at the level of chloroplasts and peroxisomes, the latter being the major site of intracellular H 2 O 2 production [5], during the photosynthetic carbon oxidation cycle and, to a lesser extent, during photorespiration, and also in the mitochondria, during the respiratory electron transport chain [2]

Deficient SHBG may contribute to the pathogenesis of inflammation by modulating the biological effects of sex hormones (testosterone and estrogen) on peripheral tissues (liver, muscle, and fat) [120,121]

Lastly, GOT2 (also known as fatty acid binding protein 1) has been found to facilitate cellular uptake of long-chain FFAs 72 , whose accumulation contributes to hepatic lipotoxicity

Abbasi, H., Kouchak, M., Mirveis, Z., Hajipour, F., Khodarahmi, M., Rahbar, N., et al