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Graphical Abstract Similar content being viewed by others Introduction The pharmacokinetics of drugs represent a major pre-step to reflect drug response and the subsequent adverse drug reactions (ADRs)

Confocal laser microscopy and image analysis Images of bacteria, whole plant and zebrafish were taken with a Zeiss 8000 laser scanning confocal microscope (Zeiss ZEN BLACK 2.3 software), whereas images of protoplasts and mammalian cells were obtained with a Nikon Eclipse Ti with C2 Plus confocal laser scanning microscope (NIS-Elements imaging 5.01

Severe encephalopathy associated to pyruvate dehydrogenase mutations and unbalanced coenzyme Q10 content

The present narrative review synthesizes peer-reviewed literature, clinical trial data, and select pipeline updates on metabolic and molecular therapies for HCU