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We limit the rate at which you can have a B12 injection to every 28 days for 3 months and then one injection every 3 months

If you have a history of B12 deficiency, malabsorption issues, or are vegetarian/vegan with marginal B12 status, the weekly B12 injection provides protection during the high-risk period of rapid weight loss

It also means allergic reactions are unlikely, though not impossible, since any foreign substance can theoretically trigger sensitivity in susceptible individuals

In April 2015, another study was published in CMAJ Open that linked PPIs to a threefold increase in the risk of developing acute interstitial nephritis and a higher risk of acute kidney injury in older adults as compared to their peers who did not take the medicines