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Description

Functional assays identified hepatocyte growth factor (HGF) and its primary receptor cMet as critical in MSC-stimulated recovery in EAE, neural cell development and remyelination

When these receptors activate, fat cells release stored lipids for energy use

Moreover, ablation of these genes leads to the complete absence of hypaxial muscles (diaphragm, limbs, tongue), reflecting that HGF-MET have a pivotal role in proliferation and motility of these muscle progenitors (Birchmeier and Gherardi, 1998)

Effects on biological aging markers and cellular health emerge over months and may continue improving during off-cycle periods as activated cellular processes continue operating