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It's probably people who didn't want kids

Panic episodes among patients with diabetes

Free radicals inflict damage upon biofilms, disrupting the intracellular milieu and precipitating cellular senescence and demise (126)

However, heightened levels of ROS, which overpower cellular antioxidant and repair capacities, can trigger oxidative stress in cells, directly causing oxidative damage to all biomolecules within the cellular environment (including proteins, lipids, and DNA), and thus contribute to the development of aging and related diseases (Dizdaroglu and Jaruga, 2012