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J Nat Prod 69(3):460463 Prostate cancer statistics| World Cancer Research Fund International [Internet] [cited 2023 Jun 27]

Therefore, iron has a significant role in enhancing cellular ferroptosis sensitivity (Feng and Stockwell, 2018)

It is recognized as the key to destroying fatty acid hydroperoxides ( Ferrozois, a new form of regulation of cell death, is primarily attributed to cellular lipid peroxidation (LPO) due to insufficient or absent GPX4 activity, ultimately causing cell death ( 2 O 2 ) to water (Ursini and Maiorino, 2020)