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Trying to reduce the oxidative stress present, they used antioxidants like NAC (increase glutathione), metformin (increase SOD2 expression), and liproxstatin-1 (reduce lipid peroxide levels) in cell cultures and found that NAC and metformin was able to reduce immune activity to some extent

It is also not yet known whether such dysbiosis leads to ME/CFS, or whether it is a consequence of the metabolic and immunologic changes that occur in the disease (201)

ONeill CH, Scoggins CR

1.2 Distinctive contribution of the present review Several previously published reviews have summarized the biological activities of natural compounds and dietary supplements in breast cancer