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Instead, using kratom could lead to dependency and withdrawal symptoms of its own

Further in vitro investigations using human vascular endothelial cells confirmed the increased expression of VEGFR2 mRNA and protein induced by BPC 157, though not VEGF-A (Hsieh et al

A consistent pattern emerges: evidence is mostly limited to animal studies human studies, where they exist, are small and short-term there are no high-quality trials reflecting real-world use, including combinations, higher doses or long-term administration

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