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It's a systemic metabolic intervention

By genetically appending a specific PS to the target RNA, the chimeric transcript is preferentially recruited during intracellular assembly, effectively creating a molecular selectivity filter that prioritizes target cargo over the dense background of host cellular transcripts (Segel et al., 2021)

Moreover, use of a rutin and ascorbic acid mixture more effectively prevented the UV radiation-induced oxidation of low density lipoprotein (LDL) and their cytotoxic effects than either ascorbic acid or rutin used separately [55]