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When all DSBs are repaired, the diplotene stage starts: the synaptonemal complex is dismantled and chimeric homologous chromosomes are only joined by chiasmata , at the crossover sites, ready to be separated by the mitotic spindle during the end of meiosis I

The MAE was recalculated at each step to assess how removing additional proteins affected predictive accuracy

Also, know what the side effects are and when to report them

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