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This bacterial defence mechanism has been shown to promote an anti-inflammatory response and induce a disease-tolerant immune response ( Psuedomonas aeruginosa and Staphylococcus aureus utilise itaconate as a carbon source to establish a persistent infection and support the development of biofilms ( Figure 1B )

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received research grants from Gilead Science and Pilant Therapeutics

Zhang L, Wu M, Yu D, Teng Y, Wei T, Chen C, Song W (2018) Identification of glutathione peroxidase (GPX) gene family in Rhodiola crenulata and gene expression analysis under stress conditions