diethyl maleate glutathione depletion

diethyl maleate glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: Implications for systemic disease and immunosenescence AOP-Wiki

Name: diethyl maleate glutathione depletion inhibits dendritic cell maturation and delayed-type hypersensitivity: Implications for systemic disease and immunosenescence AOP-Wiki
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AOP Wiki Diethyl maleate 97 141 05 9 REGULATION OF GLUTATHIONE SYNTHESIS PMC Hepatic transcriptome and proteome responses against diethyl maleate induced glutathione depletion in the rat Archives of Toxicology Springer Nature Link

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Description

This simple, two-part rule is a cornerstone of good lab practice

When catalyzed by GST, the prodrug releases cytotoxic compounds

CL can be spread through physical contact of wounds and pus, through brushes and clippers, and through anything in the barnyard that pus may have touched, such as feed, equipment, fences and structures